Welcome to the Intellegens newsletter, where we share the latest news, developments, and achievements from the team at Intellegens.
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Webinar – Oligonucleotide manufacturing
With high specificity and the ability to treat a broad range of diseases, oligonucleotides are poised for a significant impact as therapeutics. But there are currently few products on the market and manufacturing knowledge and experience is limited outside of a small number of specialist companies. In this webinar, we’ll introduce Alchemite™ for Oligonucleotide Manufacturing, developed through a two year collaboration between Intellegens, the Centre for Process Innovation (CPI), and pharmaceutical and biotech partners. You’ll see how Alchemite™ is helping to optimize process parameters, generate new insights, and reduce critical impurities in the development of new oligonucleotide processes. Dr Giacomo Padroni of CPI will share experience from real oligos projects. Dr Charlie Phillips of Intellegens will provide a live demo of the system and answer your questions. Join us to see how machine learning can enable routine process optimization with less input from senior experts, provide researchers with valuable guidance, and capture vital organizational knowledge.
White paper – Targeted models
Machine learning shows great potential to design and understand formulations, chemicals, materials, and biopharmaceuticals. Being focused on the end goal is key: to find the mixture that will fulfil target specifications such as maximizing strength, minimizing cost, or minimizing carbon footprint. This paper introduces a machine learning workflow that uniquely exploits the target specification to train a machine learning model that is optimized for this specific goal. This allows a 5x increase in performance over a model trained for accuracy over all formulations, saving time and money in the design process.
Case study – FUCHS on lubricant formulation
FUCHS, a global leader in lubricant technology, has used Alchemite™ machine learning to accelerate its formulation development. At last month’s webinar, Dr Richard Bellizzi from FUCHS discussed how machine learning has been applied to fluids for pipe coatings, hydraulics, metal working, and shock absorbers. In an example project to adapt a product to a new market segment, a 50% performance improvement was achieved. The use of adaptive experimental design approaches also enabled FUCHS to hit their target faster.
Alchemite™ now knows chemistry!
An exciting new feature is now out for chemistry-focused users of Alchemite™ – add SMILES string descriptions of your molecules and Alchemite™ understands their chemistry! Alchemite™ calculates chemical descriptors for each SMILES string in a dataset. These chemical descriptors are then used throughout Alchemite™, making predictions and experimental designs chemically aware. As an added bonus you can visualize molecules within Alchemite™. You can watch a video of our Dr Bogdan Nenchev demonstrating these new tools.
Blog – Build or buy?
It’s one of the most common questions wherever technology is applied in business – do I buy it or build it myself? Machine learning for R&D is no exception. Our latest blog considers some of the questions that might tip the balance.
A glimpse of the future: Agentic AI
Earlier this month, Dr Joel Strickland gave a fascinating glimpse into the future as he shared insight and ongoing development work at Intellegens in the area of agentic AI. If you missed the webinar, you can now view the recording online. Hear about the latest agentic trends and see a demonstration of a prototype product applying agentic workflows to chemicals and materials R&D.
Connect with us at ACS
Connect with us at the Fall meeting of the American Chemical Society. You’ll find us at booth 1940 in the exhibition throughout the show. And catch our presentation in the Pitch Lab session. We’d love to discuss how machine learning can accelerate your chemistry and formulations research and development. We can show you the new SMILES and chemical descriptor functionality, supporting chemistry-aware machine learning.
Connect with us at these upcoming events.
17-21 Aug – ACS Fall Meeting (Washington, DC). Find us on booth 1940.
18 Sep – Alchemite™ User Group Meeting (Online). Open to all users – look out for an email invitation or contact us.
23 Sep – Webinar – How machine learning can accelerate oligonucleotide process development (Online).
16-17 Oct – Advances in the Digitalisation of the Process Industries (Manchester, UK). Hear our talk on automating process R&D.
11 Nov – SCS Formulation: Creating Cosmetics (Coventry, UK). Speaking on adaptive experimental design.
